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NERVOUS SYSTEM, ORGAN SYSTEM - Coggle Diagram
NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM
BRAIN
SPINAL CORD
PERIPHERAL NERVOUS SYSTEM
AUTONOMIC NERVOUS SYSTEM
SYSTEM
PARASYMPATHETIC
FUNCTION
under stress
NOT for life in a controlled enviroment
ANATOMY
PREGANGLIONIC
#
brain stem
#
CN III
CN VII
CN IX
CN X
sacral spinal cord
#
S2-S4
limited branching = localized response
POSTGANGLIONIC
#
peripheral ganglia near innervated structure
terminal ganglia
intramural ganglia
innervate adjacent effector organ
fiber post < pre
NEUROCHEMISTRY
NEUROTRANSMITTER
Ach
ACh
NEJ = neuroeffector junction
NEUROTRANSMISSION
synthesis and storage of NT
exocytosis = release NT
diffusion
1 more item...
short duration response
fast
enzymatic inactivation
AChE = acetylcholine esterase
rapid hydrolysis
1 more item...
RECEPTORS
CHOLINERGIC
muscarinic acetylcholine receptors
GPCRs
M2 :no_entry: :<3:
M3
Gq
1 more item...
M1 - modulatory
M4 and M5 CNS
nicotinic acetylcholine receptors
N neural
ligand gated ion channel
binding of Ach to NAchR
ion channel open
1 more item...
PRESYNAPTIC
presynaptic alpha 2 receptors
postganglionic nerve terminal
:arrow_down: NT release
SYMPATHETIC
FUNCTION
required for life
in controlled environment
fighting disease = reflex bronchoconstriction when irritants enter lungs
ANATOMY
POSTGANGLIONIC
peripheral ganglia near spinal cord
ganglia near spinal cord
prevertebral ganglia
paravertebral ganglia
fiber post > pre
PREGANGLIONIC
thoracic
#
lumbar L2/L3
#
branch extensively = widespread response
NEUROCHEMISTRY
NEUROTRANSMITTER
ANDRENAL MEDULLA
ACh
adrenal medulla
1 more item...
1 motor neuron system
Ach
ACh
#
NEUROTRANSMISSION
synthesis and storage of NT
release NT by exocytosis
diffusion of NT to postsynaptic cell
1 more item...
slow
NE reuptake
through NET
Na+ dependent amine transporter system
recycle NE
1 more item...
sustained duration response
RECEPTORS
CHOLINERGIC
nicotinic acetylcholine receptors
N neural
#
on postganglia
ligand gated ion channels
muscarinic receptors
NEJ
M3
#
ADRENERGIC
N neural on adrenal medulla
ON EFFECTOR ORGAN/ NEJ
ALPHA
ALPHA 1 = Gq
#
ALPHA 2 = Gi modulatory functions
BETA
BETA 1 = Gs
#
#
BETA 2 = Gs
PRESYNAPTIC
presynaptic alpha 2 receptors
postganglionic nerve terminal
:arrow_down: NT release
SOMATIC NERVOUS SYSTEM
soma everywhere on spinal cord
one fiber
NMJ
neuromuscular junction
Ach
#
N muscle - nicotinic acetylcholine receptors
EPP end-plate potential
SKM contraction
ORGAN SYSTEM
STRIATED MUSCLE
SKELETAL MUSCLE
CARDIAC MUSCLE
VENTRICLES
BARORECEPTOR
LOCATION
CAROTID SINUS
RESPOND TO STRETCH
increase blood pressure
stimulation = stretch of blood vessels
:arrow_double_up: CN XI + CN X
NTS
areas in medulla
decrease sympathetic stimulation heart + blood vessel
increase parasympathetic stimulation of heart
SMOOTH MUSCLE
SYSTEM
GI TRACT
URINARY TRACT
BLADDER
SPHINCTER
LUNGS
EYES
BLOOD VESSELS
SWEAT GLAND
GRANULAR SECRETION
RENAL
:arrow_double_up: renin secretion