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Non-Neoplasia 6 - Coggle Diagram
Non-Neoplasia 6
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Clinical features occur both within gingival or alveolar soft tissue. The central giant cell granuloma occurs within the maxilla or mandible. most common in the anterior segment and mandible than the maxilla. primarily occur in females and children under 30 years. Patients may complain of discomfort, bi=ut pain is not a common feature
Radiographic The lesion is slow-growing and destructive, a unilocular or multi ocular radiolucency in the bone. The borders may be either sclerotic or ill-defined. Divergence of the roots of teeth adjacent is a common feature
Non aggressive type is small, asymptomatic, does not cause root resorption or cortical perforation.
Aggressive type is large, painful, destructive, and cause root resorption and cortical perforation
Radiographic appearance referred to as a "cotton wool" appearance. in eariler stages is not so spacific. Hypercementosis, loss of the lamina dura, and obliteration of PDL may also occur.
Treatment: Biphosphate, other treatment involve osteoclast inhibitors. This disease is slowly progressive. complication include fracture of involve bone and development of malignant tumors (osteosarcoma) Heart disease is a rare complication of Paget disease of bone
Diagnosis involves the clinical, radiographic, and histopathologic features, and laboratory evaluation is important in establishing the diagnosis. The serum alkaline phosphate level is significantly elevated in active disease.
GIGI
Paget disease of bone is a chronic metabolic bone disease. It is characterized by abnormal bone metabolism, including resorption, osteoblastic repair, and remineralization of bone. The cause is unknown. The disease occurs commonly in men over the age of 50. The maxilla is more commonly affected than the mandible.
Clinical manifestations of Paget disease of bone involve painful and enlargement of the affected bone. Can cause head pain, dizziness, deafness due to the impingement of cranial nerves. Edentulous patients may complain that the denture no longer fit.
Treatment by surgical removal may occasionally recur. Successful with intralesional corticosteroid injection has been reported.
In patient with hyperparathyroidism, these lesions have been called a brown tumor, the lesion are not surgically removed because they resolve when the disease is successfully treated.
(GIGI) Central Giant Cell Granuloma is an intraosseous lesion of unclear pathogenesis. Composed of well-vascularized fibrous connective tissue containing many multinucleated giant cells