Cause: Unknown. linked to genetic mutations, the earlier the mutation the more severe the disease.
Microscopically: Benign fibro-osseous lesion, vascularized, cellular fibrous connective tissue with irregular trabecule of bone emerging from the connective tissue.
Clinically: Painless, progressive, unilateral enlargement of the maxilla or mandible, may result in malocclusion, displacement of adjacent teeth, or tipping.
Radiographically: Classically appears as a diffuse radiopacity resembling "ground glass"; Difficult to determine the periphery of lesion from regular bone
Diagnosed: Clinically, radiographically, and microscopically.
Treatment: Treated surgically bu recountouring the bone. No treatment exist for severe or progressive polystotic fibrous dysplasia.
Types: Monostotic Fibrous Dysplasia and Polyostotic fibrous dysplasia.