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Brucellosis - Coggle Diagram

- - - - GI trat
      - respiratory tract
      - veneral
      - abrasion contaminantion
      - mucous membranes
    - - placenta
      - aborted fetuses
        
        lead to abortion storms
  - - - mammary glands
      - reproductive tissue
        
        high levels of erythiols
        
        endometrial ulcers
        
        lesions on wall of uterus
        
        destruction of placental cotelydons
      - GI tract
    - - late abortion
      - weak calves
      - epididymitis
      - orchiditis
      - sterility in bulls
  - - - Brucella Ag
      - complement fixation
      - ELISA
      - agglutination
    - - milk ring test
        
        pooled milk
        
        stained killed Brucellosis added to sample
        
        if infected, blue ring forms
        
        bulk tank tests
      - card test
    - - phage
      - biochemical typing
      - tissue
        
        fetal
        
        lung
        
        placenta
        
        FA Ab
        
        smears
        
        blood
      - plates must be kept for several weeks
    - - differentiate b/w IgG and IgM
        
        ELISA
        
        rivanol precipitation
        
        culture
    - - if positive, alert state board
      - if negative, tag
  - - - attenuated
      - adjuvanted bacterin
      - RB51 strain
        
        live
        
        mutant
        
        no Ab formation
      - protocols
        
        vaccinate female calves 4-10mo w/ RB51
        
        bulls, pregnant cows not vaccinate
- - - - vaginal
      - uterine
      - secretions
      - testicles
      - seminal fluid
  - - - none
    - - orchitis
      - epididymitis
      - sterility
  - - - up to 3 mo after becoming infected
    - - shed up to 6 weeks after
  - - - must be followed by confirmatory test
    - - blood
      - semen
  - - - euthanize positive dogs
    - - isolate
      - s/n
      - treat early
      - sollow-up serology
      - euthanasia should be considered
- - - - semen
- - - - infrequent
      - mummified fetuses
  - - - intermittent for 2-4y
- - - - milk
      - fetus
      - vaginal