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S5- MAJOR NUTRITIONAL STUDIES - Coggle Diagram
S5- MAJOR NUTRITIONAL STUDIES
Food groups
Nuts
Pllant protein
Peas
Tofu
lentils
beans
Viscous Fibres
Apple, strawberry, oatmeal
3 groups
Portfolio
Red 28.6% in LDL
2, Lovastatin group
Lowered LDL by 30% (no sig difference)
control (low sat fat) 7% red LDL
Mind movie- port bottle me hakro maru almonds (ne. fruit and fibre) fagay ane byo wado bhodo jo maro statins fagay under
also CRP /inflammatory reduction in Portfolio diet
DASH
"Dietary Approaches to Stop Hypertension"
Standard DASH diet. < 2,300 milligrams (mg) of sodium/ day.
Lower sodium DASH diet. You can consume up to 1,500 mg of sodium a day.
EAT
Veg
Grains
low Gi fruits
Lean meats
nuts
Healthy oils/fats
Don't eat-
salt
processed foods
OUTCOME
The DASH diet has been well studied in many clinical trials, and most of them have been associated with lowering blood pressure. Further, there is evidence to show that the DASH diet also lowers the risk of adverse cardiac events, stroke, type 2 diabetes, and obesity.
ORNISH PROSTATE DIET/ GEMINIAL STUDY 2008
study to determine gene expression changes in men with low risk prostate ca
33 MEN.
3 day intensive retreat followed by 3 month o/p programme
intervention = low fat/plant based diet
RESULTS
PSA
Intervention group 6.3 DECREASED TO 6
control group 6.3 INCREASED TO 6.7
Prostate cancer growth
Intervention- REDUCTION BY 70%
CONTROL 9% REDUCTION
ORNISH CORONARY ARTERY DISEASE DIET
46 PEOPLE. 2 GROUPS pts with CAD
USUAL CARE
Intervention group
vegetarian
aerobic excercise
stress management
psychosocial support
low fat
smoking cessation
RESULTS
5 YEAR STENOSIS
Intervention group (not taking statins)
RELATIVE REDUCTION of 7.9%
Control group (taking statin)
Relative increase of 27% stenosis
Control (no statin)
Inc stenosis of 47%
Cardiac events
Control=45
intervention 25
risk ratio is 2.47
in intervention group- stenosis got even better after 5 years, The conbtrol group got worse
angio at baseline, 1 and 5 years.
NO STATINS USED IN EXPERIMENTAL GROUP
LYON HEART STUDY
, subjects following the Mediterranean-style diet had** a 50% to 70% lower risk of recurrent heart disease- OUTCOME MEASURES OF (1) cardiac death and nonfatal heart attacks; (2) the preceding plus unstable angina, stroke, heart failure, and pulmonary or peripheral embolism; and (3) all of these measures plus events that required hospitalization.
330 control= american diet
300 intervention- med diet
protective effects at 4 years
SECONDARY PREVENTION after MI
Esselstyn Diet for CAD
very low fat, plant based diet
reversed and prevented major cardiac events in 177 adherant patients
In adherant pts cardiac events were 0.6%
in non-adherant patients cradiac events were 62%
BILL CLINTON
CHIP DIABETES
Effective tx diabets
ROI in 3 months.
