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Sickle Cell Anemia Sickle Cell Anemia Picture, ` - Coggle Diagram
Sickle Cell Anemia
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Incidence/Prevalence
1 out of every 1,000 Hispanic Americans infants are born with sickle cell
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Approximately 100,000 Americans Affected
Approximately 300,000 infants are born with sickle cell anemia annually in the Unites States
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176,000 people worldwide die annually due to sickle cell complications
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Treatments
Medications
Hydroxyurea
Administration
Do Not Cut, Crush, or Chew
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L-Glutamine
Therapeutic Advantages
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Increases the proportion of nicotinamide adenine dinucleotides in sickle cell erythrocytes which reduces oxidative stress
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Dosage
Recommended: 5 - 15 grams per dose mixed with 8 ox of cold or room temperature beverage or 4 - 6 oz of food before ingestion
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Adverse Effects
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Back, Leg, Feet, Arm, or Hand Pain
Crizanlizumab
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Therapeutic Advantages
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Inhibits the production of the P-selectin glycoprotein preventing the adhesion molecule process that leads to blood flow occlusion
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Voxelotor (GBT440)
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Administration
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Do Not Cut, Crush, or Chew
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Diagnostics
Newborn Blood Test
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Positive Test Results
Assessing stroke risk at the age of two using ultrasound technology to determine blood flow continuity
Prenatal/Unborn Test
Samples of the amniotic fluid in the mother's womb can determine whether or not the child has sickle cell anemia
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