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Alzheimers disease - Coggle Diagram

- - - - used to rule out tumors, hemorrhage, stroke, and hydrocephalus
      - identifies loss of brain mass associated with Alzheimers
    - - used to rule out tumors, hemorrhage, stroke, and hydrocephalus
      - identifies loss of brain mass associated with Alzheimers
    - - Amyloid PET imaging
      - Tau Pet imaging
      - Fluorodeoxyglucose (FDG) PET
- - - - BRAIN ATROPHY
        
        kills neurons
        
        loss of long-term potentiation
        
        neurotoxicity in the hippocampus
        
        neurotoxicity in the entorhinal cortex
        
        damages synapses
  - - - BRAIN ATROPHY
        
        displaces organelles and interferes with cell function
        
        distort spacing of microtubules
        
        diminish nutrition of axon terminal
        
        impair axon transport
        
        Brain atrophy
        
        diminish nutrition of dendrites
- - - - chromosome 21
        
        APP14
        
        PSEN1
        
        PSEN2
    - - chromosome 19
        
        APEO4
- - - - boost levels of cell-to-cell communication
        
        galantamine
        
        donepezil
      - improve neuropsychiatric symptoms
        
        rivastigmine
    - - used alongside cholinesterase inhibitors
        
        namenda
      - improves brain cell communication
    - - antipsychotic meds for hallucinations, delusion, and aggression
        
        Aripiprazole
        
        Haloperidol
        
        Aripiprazole
      - Anxiolytics for anxiety and restless behavior
        
        lorazepam
        
        oxazepam
      - antidepressants for irritability and depressed affect
        
        fluexetine
        
        sertraline
        
        tranzodone