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Mycotic: Inflammation and Infection: Neuropathology - Coggle Diagram
Mycotic: Inflammation and Infection: Neuropathology
systemic
hematogenous disemination of fungal yeast
seeding of leptomeninges
species
Blastomyces dermatitides
Histoplasma capsulatum
Coccidioides immitis
Microsporida
Encephalitozoon cuniculi
rabbits
Cryptococcus neoformans
seems to have affinity for brain tissue
entry
hematogenous
direct extension from the nasal cavity
most frequently encountered CNS mycosis
50% of infected animals exhibit CNS signs
pathogenic variants
thick mucpolysaccharide capsule
not chemotactic
resists phagocytosis
minimal inflammation
CNS lesions
sold masses of organisms
minimal inflammatory response
cloud leptomeninges +/- hemorrhage
direct extension from the nasal cavity
type of inflammatory exudate may vary
granulomatous
pyogranulomatous
opportunistic
debilitation or immunosuppression results in tissue invasion
hematogenous
direct extension
septic thromboli
agents
Aspergillus
sp.
Mucor
sp
Rhizopus
sp
Candida albicans
