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Lyme Disease in Horses - Coggle Diagram
Lyme Disease in Horses
challenges
sparse literature
extrapolated from human/dog medicine
ID tests are invasive and costly
diagnosis is rarely definitive
seroprevalence studies
high in endemic regions
approx. 60% in MN
majority of infections do not progress to clinical dz
geographic range is increasing
clinical signs
equine vet reported
stiffness/lameness
+/- synovial effusion
behavioral changes
uncommon signs
fever
neck/back pain
cardiac arrhythmia
nephritis?
cutaneous pseudolymphoma
papular/nodular dermatitis
documented
uveitis
neuroborreliosis
ataxia
cranial nerve dficits
mm atrophy
behavior changes
dysphagia
laryngela paralysis
seizures
most confirmed on necropsy
no matter what, Lyme will be low on differential
treatment
antimicrobial therapy
can assist in diagnosis
not well supported due to inability to reproduce dz experimentally
tetracycline abx
UV oxytetracycline
doxycycline pobid
minocycline pobid
ocular or CNS infection
usually 4 weeks
diagnosis
Osp A
Osp C
Osp F
future directions
experimental model needed
true range of clinical signs needed
improved tests needed
determine levels of vaccine-induced Abs that confer protection against infection/dz