Please enable JavaScript.
Coggle requires JavaScript to display documents.
Exploring the catalytic properties of D-Amino acid metabolic enzymes for…
Exploring the catalytic properties of D-Amino acid metabolic enzymes for drug discovery
Instrumental expertise
HPLC 3
Spectrophotometr
FPLC 4
Mass spectrometry
SDS-PAGE 2
DNA Sequencer
Alanine Racemase
Target for D-Alanine production
Ubiquitous among prokaryotes
Target for drug discovery
Collaborators
Pharmaceutical industries
Professors and research students
Research Institutes
Disease carriers (patients)
Scientific research funding agencies
Objectives
Mechanistic pathway for drug discovery
How to characterize the enzymes
Fulfill commercial needs
How to screen for inhibitors
Data interpretation
Practical knowledge of Directed Evolution
How these drugs treat the diseases
D-Amino acid oxidase (DAAO)
Disease treatment
Target for drug discovery
Target for Industrial productions
Importance
Drug Development
Industrial production of D-Alanine
Peptidoglycan biosynthesis
Why catalytic mechanism evaluation
.
To explore the peptidoglycan pathway
To screen for inhibitors
To explore the catalytic activity