cell injury 2 - Coggle Diagram
cell injury 2
MORPHOLOGY OF REVERSIBLE CELL INJURY
accumulation of water in cytoplasm,
completely reversible change
Mucus like change by mucin
pink deposits of proteinaceous material,
intracellular and extracellular hyaline
1.the study of the forms of things.
2.a particular form, shape, or structure.
ACCUMULATION OF OXYGEN DERIVED FREE RADICALS
Free radicals have single unpaired electron in an outer orbit and are highly reactive.
Superoxide oxygen (O’2)
Hydrogen peroxide (H2O2)
Halide reagent, etc
CYTOTOXICITY OF FREE RADICALS
leads to membrane damage and
destruction of organelles
Oxidation of proteins:
this causes fragmentation of polypeptides
breaks single strands of nuclear and mitochondrial DNA,
which can lead to malignant transformation of cells
interacts with cytoskeletal elements and
interferes with ATP production