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Oxygenation: AECOPD - Coggle Diagram
Oxygenation: AECOPD
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Pathogenesis
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As the inflammatory cascade occurs, lung elasticity decreases (beyond the chronic impairment) and edema in the bronchiolar walls develop causing bronchoconstriction contributing to SOB as air movement is restricted by bronchoconstriction.
Mucus production is increased further impaired gas exchange as alveoli can't exchange through mucus causing alveolar hypoventilation
As air movement is limited through the constricted bronchioles and exchange is limited in the alveoli, WOB increases, the patient feels SOB, and hypercapnia and hypoxia occur as O2 can't get in the blood and CO2 cannot leave.
Possible pulmonary hypertension as pulmonary arterioles constrict secondary to hypercapnia or pneumothorax can occur
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