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Antidepressants - Coggle Diagram
Antidepressants
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Tricyclics
Inhibit re-uptake of norepinephrine and serotonin by blocking the transporters responsible for re-uptake
Increasing concentration of neurotransmitters in the synapses and triggering further neurotransmission
Uses
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Chronic pain (fibromyalgia, reflex sympathetic dystrophy)
Work by blocking re-uptake into the nerve endings and increasing their levels in the pain control pathways
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Cautions
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Have antimuscarinic activity that blocks activity of muscarinic acetylcholine receptor so reduces intenstinal mobility
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Presynaptic alpha2-adrenoreceptor antagonist/ noradrenergic and specific serotonergic antidepressant (NaSSA)
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