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MLS, Beta-lactams, aminoglycosides, Rifampin, Fluoroquinolones, Anti…

- - - - large Vd
        
        good tissue penetration
        
        excreted in bile
        
        effective against Mycoplasma, Bracyspira
        
        gram +
        
        effective against anaerobes and aerobes
        
        2 more items...
        
        effective against anaerobes only
        
        1 more item...
        
        good oral bioavailability
        
        gram + and -
        
        1 more item...
- - - - aerobes and anaerobes
        
        low Vd
        
        weak acids
        
        time dependent T>MIC
        
        gram + and -
        
        extended spectrum penicillins
        
        2 more items...
        
        2nd generation cephalosporins
        
        1 more item...
        
        4th generation cephalosporins
        
        1 more item...
        
        carbopenem
        
        1 more item...
        
        potentiated penicillins
        
        1 more item...
        
        gram -
        
        3rd generation cephalosporins
        
        1 more item...
        
        monobactam
        
        1 more item...
        
        gram +
        
        benzylpenicillins
        
        1 more item...
        
        1st generation cephalosporins
        
        1 more item...
- - - - gram -
        
        moderate VD
        
        water soluable
        
        excreted in urine
        
        Cmax/MIC
        
        :forbidden: kidney disease
        
        4 more items...
- - - - lipid-soluable
        
        secreted in bile
        
        high resistance
        
        godo oral bioavailability in monogastric
        
        poor oral bioavailability in ruminants
        
        aerobes and anaerobes
        
        gram +
        
        some gram -
- - - - :forbidden: poultry
        
        feline retinal degeneration
        
        chondrotoxic effects in young animals
        
        large Vd
        
        Mycoplasma
        
        Chlamydia
        
        1 more item...
- - - - potentiated sulfoamides
        
        time dependent (T>MIC)
        
        oral administration
        
        good tissue penetration
        
        short half-life
        
        aerobes, anaerobes, Chylamydia
        
        2 more items...
      - sulfonamides
        
        aerobes
        
        moderate Vd
        
        good tissue penetration
        
        intemediate half life
        
        resistance common
        
        2 more items...
- - - - can be cidal
      - short PAE
      - T>MIC
- - - - :forbidden: food animals
        
        good bioavailability in monogastrics
        
        poor oral bioavailability in ruminants
        
        oral, SQ, IV
        
        gram -, some gram +
        
        anaerobes, protozoa, C.perfinges
        
        5 more items...