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Lecture 51: Autonomics of the Thorax, NO Parasympathetic to Body Wall! -…
Lecture 51: Autonomics of the Thorax
Nervous System
CNS
Brain + spinal cord
PNS
Cranial nn. (1-12) + peripheral nn.
Somatic
:red_flag:
straited voluntary muscles
Sensory :black_flag:
sharp, well localized
Cell body
outside
CNS in sensory ganglia
Synapses
in CNS
dorsal root (or spinal) ganglion
Motor :black_flag:
cell body inside CNS
Synapses on
target cell
Visceral
:fire:
(cardiac/smooth mm., + glands)
Motor
= Autonomic N.S. :explode: !
Sympathetic
(
"thoraco-lumbar"
) :star: :red_flag:
Energy expenditure "fight or flight"
Pre
ganglionic cell bodies:
lateral horn T1-L2
Post
ganglionic cell bodies: paravertebral ganglia & subdiaphragmatic ganglia
supplies
body wall/cavity
structures
Sympathetics to
Body Wall
:star:
PREganglionic
sympathetic cell bodies
confined to:
T1-L2
Lateral Horn
Visceral
structures of the body wall exist
outside
these boundaries
Resulting structure is the
sympathetic chain (trunk)
:!:
ONLY
PRE
ganglionic axons!
PREganglionic Axons
Ventral root -> spinal n. -> Ventral ramus -> White ramus comm -> Paravert. ganglion -> then
either
synapse at level (T1-T5)
preganglionic
AXONS
ascend
or
descend
, & synapse in a
higher
/
lower
paravertebral ganglion
POSTganglionic Cell Bodies
In paravertebral ganglia C1-Co!
POSTganglionic Axons
Gray ramus comm. -> ventral ramus -> then
either
stay in ventral ramus OR pass into dorsal ramus
Sympathetics to
Thoracic Organs
:star:
Preganglionic Cell Bodies
T1-T5 lateral horn
Preganglionic Axons
Ventral root -> Spinal n. -> ventral ramus comm -> Paravert. ganglion -> then
either
...
(1) Synapse at level (T1-T5)
(2) Ascend & synapse at HIGHEr paravertebral ganglion (C1-C8)
Postganglionic Cell Bodies
In paravertebral ganglia (C1-T5)
Postganglionic axons
Leave paravertebral ganglia (C1-T5) as thoracic OR cervical sympathetic organ nerves
Parasympathetic
(
rest & digest
) :<3:
"cranio-sacral"
energy INTAKE
Preganglionic Cell Bodies
brainstem or S3-S4
Postganglinoic Cell Bodies
in 4 dissectible ganglia in head or near/in target orgal wall
PS axons NEVER enter body wall!
Parasympathetics to
Thoracic Organs
:<3:
PREganglionic Axons
VAGUS NERVE (CN X)
PREganglionic Cell Bodies
Brainstem
POSTganglionic Cell Bodies
walls of organs
Pre from Vagus N. join Post axons to form
PLEXUSES
! :explode:(
these supply each of thoracic organs)
POST ganglionic Axons
In the organ wall
Visceral Motor Neuron
Preganglionic
cell body
always inside
the CNS!
lateral horn T1-L2 :star:
Postganglionic
cell body
always OUTside
CNS, in autonomic ganglia
paravertebral ganglia & subdiaphragmatic ganglia :star:
Visceral Sensory Neuron
Peripheral process of axon
Cell Body
(always outside of CNS in sensory ganglia)
Central process of Axon
Synapses
in CNS
Visceral Sensory
does
NOT
always reach consciousness!
When perceived-
NEVER comfortable!
Can arise from:
-Ischemia, distension, cramping, or inflammation
does
NOT
arise from touch, temperature, or cutting
Usually follows pathway of sympathetic outflow to an organ
Exception
= Pelvic organs
REFERRED PAIN
:explode:
Defn:
"True visceral sensation is misinterpreted by CNS as somatic sensation"
Reason:
Dorsal horn has
alternating
alyers of somatic & viscero-somatic cell bodies (NO purely visceral cell bodies!)
HEART ATTACK-
Male
:explode:
Often assoc. w/dermatomes
T1-T5
Pain coming from left arm; chest; back
HEART ATTACK-
Female
:explode:
Women do
NOT
show squeezing chest pain
or
pain radiating down arm!
CAN show pain in:
-neck
-jaw
-upper back
-chest/lower chest
-upper abdomen
Symptoms:
Fainting, indigestion, & extreme fatigue
CONSEQUENCES
(British Heart Foundation)
Delay
seeking medical
help
b/c don't recognize symptoms
W
50% more likely
to receive
WRONG initial diagnosis
!
Women
LESS likely
to receive
potentially life saving treatment
in timely way
LESS
likely
to be p
rescribed meds
to help
prevent
2nd MI
NO Parasympathetic to Body Wall!