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Viral Infections of CNS - Swine - Coggle Diagram
Viral Infections of CNS - Swine
pseudorabies/Aujeszky's Disease
Alphaherpesvirus
enveloped
neuclocapside
surface glycoproteins
dsDNA
latency
signs
young pigs
CNS
ataxia
lateral recumbency
diffuse meningoencephalitis
"mad itch"
respiratory disease
reproductive diseaes
abortion
mummies
stillborns
small necrotic foci on liver and spleen
secondary hosts
neurological
severe pruritis
fast progression
pathogensis
proliferates in nasopharynx and tonsils
spreads to regional LNs
short viremia
shedding
2-5d afer infection
latency
in trigeminal ganglia and tonsil
reactivated by
stress
dexamethasone stop
hosts
swine
secondary/dead-end hosts
companion animals
cat
dog
farm animals
cattle
sheep
goats
wildlife
REPORTABLE
PRRSV
virulent strains can cause cerebral vasculitis
high mortality
Teschovirus (PTV)
Teschen
high mortality and morbidity in all age groups
signs
paralysis
convulsions
coma
death
FAD
Talfan
less severe signs
young pigs only
posterior paralysis
signs
polioencepahomyelitis
often asymptomatic
fever
ataxia
convulsions
paralysis
pathogenesis
replicaton in the gut and mononuclear cells of lamina propria
hematogenous spread to CNS
transmission
fecal-oral
persistent in environment
diagnosis
virus isolaiton from brain, spinal cord
PCR
AB tier by serology
prevention/control
quarantine
movement control
biosecurity