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Innate Immune Response - Coggle Diagram
Innate Immune Response
Inflammation
Sterile/non-infectious
Detected via DAMPs (= Damage-Associated Molecular Pattern) secreting IL-1, IL-6, IL-10, TNF, IL-1beta, NFkB
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Non-sterile/infectious
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Detected via PAMPs (= Pathogen-Associated Molecular Pattern) secreting IL-1, TNFalpha, IL-6, IL-12
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Complement system
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Clearance of microbes
Opsonization = making pathogens more susceptible to phagocytosis by decorating their surface with molecules that phagocytes can bind
Coating by 3b
Phagocytosis
Phagosome + lysosome = phagolysosome
Cytolysis/cell lysis = water moves into the cell, thereby increasing or expanding the cell
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Agglutination = cell-bound antigen
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