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Altered hormonal & metabolic function, impairment of the hypothalamic-…
Altered hormonal & metabolic function
SIADH
Treatment
-Water restriction
Clinical Manifestations
-Anorexia
-Vomiting
-Disorientation
Diagnostic Criteria
-Hyponatremia
-Hypotonicity
-Decrease urine volume
too little or too much hormone that is being secreted and produce
Is not producing active hormone, receptor binging adequate, target cell responding to the hormone
Diabetes insipidus
Diagnostic Criteria
-Enlargement of the bladder
-Dehydration
Treatment
-Hydration
-Desmopressin
Clinical Manifestations
-Excessive thirst
-Polyuria
Hyperthyroidism
-Impairment of: endocrine gland, negative feedback loop, hormone metabolism inactivation and elimination
-Producing too little or too much hormone
-producing active hormone
Hypothyroidism
Treatment
-Levothyroxine
-Normalizing TSH levels
Diagnostic Criteria
-Lab studies of sensitive TSH assay
-Antithyroglobulin test
Clinical Manifestations
-Impaired reproduction
-Myxedema
Clinical Manifestations,
-Goiter
-Exophthalmos
-Weightloss, agitation
Treatment
Reduce thyroid levels through:
-Full abalation of the thyroid gland
-radioactive iodine
Diagnostic Criteria
-Measurement of serum-free thyroxine
-Elevated serum levels of T3 and T4
Cushing syndrome
Treatment
-Surgery
-Radiation
-Corticosteroid medication
Diagnostic Criteria
-Imaging studies to locate tumor
Clinical Manifestations
-Excessive circulating glucocorticoids
Addison disease
Diagnostic Criteria
-Analysis of electrolyte levels presenting hyponatremia and hyperkalemia
-Depressed levels of serum corticosteroid
Treatment
-Isotonic IV fluid replacement w/ hydrocortisone sodium succinate
-Oral replacement of glucocorticoid and mineralocorticoid
Clinical Manifestations,
-Insufficient levels of steroid hormones
impairment of the hypothalamic- axis