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Multisystemic Diseases of LA: Corynebacterium pseudotuberculosis - Coggle…
Multisystemic Diseases of LA:
Corynebacterium pseudotuberculosis
characteristics
gram + rods
aerobic
2 types
soil dwelling
diagnosis
serology
culture
worldwide
small ruminants
aka
caseous lymphadenitis
pyogranulomatous abscesses in LNs
external
mandibular
parotid
prefemoral
prescapular
more common in goats
internal/visceral
more common in sheep
locations
lungs
kidneys
mediastinal
bronchial
mesenteric
lumbar LNs
less likely to have external abscesses
higher fatality rate
weight loss common
if in thoracic cavity
tachypnea
exercise intolerance
dyspnea
chronic cough
diagnosis
transtracheal wash (TTW) isolation
LN aspirate culture
dangerous because it releases infectious material from pus
serological tests
synergistic hemolysis inhibition
ELISA
challenging to interpret
treatment
benign neglect
lancing and draining
systemic antibiotics
intralesional antibiotics
en bloc
surgical removal
CLA
corny
internal or external abcesses
ulcerative lymphangitis
bovine
cutaneous exXxcoriations
large plaques
laterally exposed areas
face
neck
thorax
flanks
lymphangitis
mastitis
visceral or mixed infections
management problems contribute
equine
entry
abrasions, wounds
dermatitis
insect vectors
3-4w incubation
persist in environment for months
no vaccine
manifestations
external abscesses
internal abscesses
8% of infections
high fatality
most commonly affected organs
liver
spleen
kidney
lungs
ulcerative lymphagitis
least common in US
limb swelling
draining tracts
cellulitis
lameness
fever
lethargy
aggressive treatment
diagnosis challenging
long-term antimicrobials needed