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mesoderm differentiation (week4), mesoderm, somite growth regulation:
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somite growth regulation:
formation: increase NOTCH protein during development +decrease after growth
boundaries establishment: retionic acid (high at cranial region)+FGF8 , WNT3a (high at caudal region)
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regulation:
1.(lateral) MYOD expression via WNT + BMP4 (lateral plate mesodem)
- (mediall) MYF5 expression via WNT
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