Please enable JavaScript.
Coggle requires JavaScript to display documents.
Sickle Cell Disease - Coggle Diagram
Sickle Cell Disease
Clinical Manifestations
jaundice
anemia
pain (chest, extremities, abdomen)
tissue ischemia
hemolysis
vaso-occlusion
stroke
priapism
organ damage (spleen, kidneys, liver)
neurocognitive decline
intracranial hemorrhage
Treatment
avoid precipitating factors
CBC
pain management (opiates)
immunizations
blood transfusion
Pathophysiology
inherited blood disease causing abnormal shape and function in red blood cells
affects hemoglobin in red blood cells
Autosomal Recessive disorder
hemoglobin A is replaced by hemoglobin S (sickled)
Diagnostic Tests
isoelectric focusing
high performance liquid chromatography
hemoglobin electrophoresis
intracranial hemorrhage