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Distemper - Coggle Diagram

- - - - infection
        
        subacute/chronic
        
        "Old Dog Encephalitis"
        
        mature dogs
        
        may not have systemic illness
        
        unflammatory demyelination not caused by viral replication
        
        presentation
        
        myoclonus
        
        involuntary mm twitching
        
        same as acute
        
        acute CDV encephalitles
        
        immunocompromised
        
        direct viral replication
        
        acute non-inflammatory demyelination
        
        signs occurs early or weeks after systemic disease
        
        immature dogs
        
        presentation
        
        chewing gum seizures
        
        ataxia
        
        hyperestesia
        
        cervical/paraspinal rigidity
        
        "fly biting"
        
        meningial inflammation
      - due delayed immune response
      - 30% of dogs
      - not treatable
      - progressive
  - - - diffuse change
      - intersitial lung pattern early
      - 2ndary bacterial infections can occur
  - - - tenesmus
      - intusssusception
  - - - acute onset blindness
      - unresponsive pupils
    - - "gold medallion lesions"
  - - - trasnplacental infections
      - hypertrophic osteodystrophy
      - HOD and juvenile cellulitis
- - - - circular lymphocytes
      - gingival scraping
  - - - IHC
      - acute infection only
    - - cannot differentiate virus vs vaccine
    - - IgM
        
        acute
      - IgG
        
        not acute
        
        vaccination
    - - acute presentation
        
        CSF
        
        cell count
        
        protein measurement
        
        increased
        
        ctology
        
        antiCDV Abs