-Allele responsible for Dz's on X-chromosome.
-Women are carriers and only affected if both X-chromosomes carry affected allele.
-Children have a 50% of inheriting the altered x-chromosome. Sons develop disease and daughters are carriers.
-skips generations
-Men whose only X-chromosome carries altered allele, will always develop the disease.
-All daughters inherit the altered X-chromosome: Carriers.
-All sons that inherit the healthy X from mom: healthy!
Ex. color blindness, hemophilia A/B. G6PD deficiency, Duchene muscular dystrophy, Lesch-Nyhan syndrome,, becker muscular dystrophy