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MICROBIAL INVASION, :warning:Myocardial hypoxia, kidney pi, :red_cross:, …
MICROBIAL INVASION
Trigger inflammatory response
cause
Secretion of histamin
cause
:arrow_up:
VASCULAR PERMEABILITY
Other tissue
Interstitial oedema :droplet:
lead to
:arrow_up: Diffusion distance
1 more item...
lead to
Pulmonary system
:arrow_up: Diffusion distance in alveoli (ARDS)
:arrow_down:PaO2 (hypoxaemia)
Stimulate respiratory center
2 more items...
:arrow_up: PaCO2 (hypercapnia)
Pulmonary cell ischaemia
cause
:arrow_down: Gaseous exchange surface area
2 more items...
:arrow_up: RR, :arrow_down: SpO2 :arrow_up: WoB, :arrow_up: Depth of respiration, :arrow_up: Breathing sound (acute); cyanosis (late stage)
cause
Production of pro-inflammatory cytokines
VASODILATION
:arrow_down: Systemic vascular resistance
:arrow_down: Global arterial pressure
Exacerbate
PRESENTATION:
initial: warm to touch, then cold to touch
Acute inflammation
cause
Endothelial damage
cause
Microvascular damage
:arrow_up: use of coagulation factor
Activation of coagulation cascade
To assist with
cause
Activation of NK cells
cause
Send Signal to sentinal cells
Exacerbate
:warning:Myocardial hypoxia
Myocardial dysfunction
Cardiac arrhythmia
Myocardial Ischaemia/infaction
Cardiovascular deterioration
:warning:DEALTH :warning:
SYMPTOMS: Angina,
radiating pain, tachycardia followed by bradicardia if fail to resusitate
KIDNEY (URINARY SYSTEM)
Kidney ischemia
kidney cellular death
Acute tubular necrosis
Acute kidney injury (AKI)
SYMPTOMS: reduced urine output, SoB, seizure
:red_cross:
:red_cross:
Exacerbate
:warning:
