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Skin physiology || jg4WE 1. Anatomy, Physiology, and Embryology of the…

- - - - As cells progress up the stratum corneum, they are shed in the process known as desquamation
- - - - it allows humans to live on dry land.
  - - - keeping out microorganisms; it is the first line of defense against ultraviolet radiation; and it contains many enzymes that can degrade and detoxify external chemicals.
      - The stratum corneum is also a semipermeable structure that selectively allows different hydrophilic and lipophilic agents passage.
      - the most obvious and most studied aspect of the stratum corneum is its ability to protect against excessive water and electrolyte loss.
      - It acts as a barrier to keep chemicals out, but more importantly, it keeps water and electrolytes inside the human body.
    - - The main lipids responsible for protection against water loss are the ceramides and the sphingolipids.
        
        These molecules are capable of binding many water molecules.