Araújo Filho, B. C., Neto, C. P., Weber, R., & Voegels, R. L. (2008). Sphenoid sinus symmetry and differences between sexes. Rhinology, 46(3), 195-199.
In this study, forty-five corpses were dissected. The findings suggest that there is an anatomical difference between male and female sphenoid sinus as the distance between sphenoid sinus ostium and anterior nasal spine is larger in male brain by 3 mms. That difference should be taken into account in surgery.