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Triaglycerol biosynthesis - Coggle Diagram
Triaglycerol biosynthesis
consume
Acetyl- CoA
ATP
NADPH
Routes of synthesis
synthesize polyunsaturated FAs
mammals cannot synthesize linoleate, 18:2(9,12), 18:3(9,12,15)
Plants and bacteria can synthesize
to
ensure membrane fluidity at reduced temparetures
Cholesterol is made from
Acetyl- CoA
Cholesterol and other lipids are carried on plasma lipoproteins
Chymlomicron
contains a high proportion of triacyglycerols
very low-density lipoprotein (VLDL)
carries triacyglycerols, some cholesterol and cholesteryl esters
low-density lipoprotein (LDL)
rich in cholesterol and cholesteryl esters
high- density lipoprotein (HLD)
contains relatively little chloesterol
no chloesteryl esters
Triacylglycerols are formed from
fatty acyl- CoA+ glycerol 3-phosphate
form
phosphatidic acid
dephosphorylated
diacylglycerol
acylated by a third molecule of fatty acyl- CoA
to
triacylglycerol