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Clexane (Side effects (Nausea, Diarrhoea, Peripheral oedema, Fever,…
Clexane
Side effects
Nausea
Diarrhoea
Peripheral oedema
Fever
Confusion
Allergic reaction
Haemorrhage
Headaches
thrombocytopenia
Administration
Sub cuteneous
Site 5cm away from umbilicus
Pinch skin and hold until needle removed
Do not rub the site
Hygiene
Appropriate disposal of sharps
Alternate sites
Air bubble at the top
ensure air bubble injected at the end to seal the medication
dosage of 40 mg
“dart” injection technique
Pharmacokinetics
Maximum bioavailability within 3 to 5 hours
100% is metabolised
by the liver
Elimination is monophasic
excreted renally
half-life of 4 hours
7 hours for repeated dosing
Prophylaxis for venous thromboembolic disease
Treatment of unstable angina and non-Q-wave myocardial infarction
Prevention of thrombus formation in the extra-corporeal circulation during haemodialysis
Treatment of acute ST-segment Elevation Myocardial Infarction
References: Med Safe. (2017). Data sheet: Clexane and Clexane forte. Medsafe. Retrieved from
http://www.medsafe.govt.nz/profs/datasheet/c/clexaneinj.pdf