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Leukocyte Recruitment (Endothelial Cells (control extravasation of…
Leukocyte Recruitment
Endothelial Cells
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secrete anticoagulants to regulate blood flow, vasoconstrictors and vasodilators
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Neutrophils
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they get activated once they are in the tissue by various stimuli (antibodies IgG and IgM, TNF-a, complement, molecules found in bacterial cell wall)
eliminate pathogens and damaged cells either through phagocytosis or through release of powerful enzymes
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once the pathogens and damaged cells have been eliminated, they undergo apoptosis within 10-24 hours of exiting circulation and are the main component of pus
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Platelets
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degranulate on contact with collagen fibres in endothelium or thrombin, a plasma protein
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