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TUBERCULOSIS (PULMONARY (SECONDARY TB (BACILLI WALLED OFF: (GRAY-WHITE,…

- - - - TUBERCLES IN LYMPHATICS
      - ENLARGED HILAR & TRACHEOBRONCHIAL NODES
      - PRIMARY FOCUS: NECROSIS IN UPPER LOBE BASE/APEX OF LOWER LOBE
    - - PULMONARY SPREAD
        
        LIQUEFATION OF CONTENTS DUE TO SUPERADDED INFECTION
        
        CONTENTS EXIT CAVITY VIA BRONCHUS & SPREADS TO HEALTHY LUNG.
      - HAEMATOGENOUS SPREAD
        
        RUPTURE OF CASEOUS MATERIAL INTO BV.
        
        PUL. ARTERY, IT SPREADS IN LUNG.
        
        PUL. VEIN, IT SPREAD THROUGHOUT BODY
        
        ORGANISMS IN BLOOD CAN RESULT IN:
        
        MILIARY TB
        
        HEAVY HAEMOTOGENOUS SPREAD USUALLY FROM EROSION OF LYMPH NODE INTO BV
        
        SUBACUTE TB
        
        FEWER ORG. INTRODUCED TO BLOOD
        
        INCIDENTAL BACTERAEMIA
        
        ORGAN TB
        
        DRAINAGE OF MEDIASTINAL LYMPH NODES VIA THORACIC DUCT INTO SUBCLAVIAN VEIN
      - HEALING
        
        LESION WALLED OFF BY FIBROSIS
  - - - GRAY-WHITE
      - CASEOUS NECROSIS
      - FIRM
    - - PROGRESS INTO CAVITY FORMATION
      - HEALINGBY FIBROSIS
      - DISTANT SPREAD
        
        HAEMOTOGENOUSLY
        
        MILIARY PULMONARY TB
        
        ENTERS VENOUS SYSTEM & CIRCULATES BACK TO LUNGS
        
        SYSTEMIC MILIARY TB
        
        ENTERS SYSTEMIC ARTERIAL CIRCULATION