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Bronchiectasis (MORPHOLOGY (mucosa (polypoid hyperplasia, squamous…
Bronchiectasis
MORPHOLOGY
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thickening by fibrosis, inflammatory oedema, infiltrate of inflammatory cells
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Development of bronchopulmonary anatomoses between venous and arterial supply d/t 2ry enlargement of vessels following it
PATHOGENESIS
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Outside airways
Healing of outer lung worsens condition of bronchioles:
absorption collapse, post-pneumonia fibrosis increase forces pulling already dilated bronchioles
DEFINITION
abnormal, permanent dilatation of the bronchi
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AETIOLOGY
Infection
measles, pertussis, adenovirus, post-pneumonic (esp Staph)
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Obstruction
tumour, foreign body, hilar node (tuberculous lymphadenopathy - usually R middle lobe)
Impaired defence
cystic fibrosis, Kartagener's syndrome (high incidence of nasal sinusitis d/t ciliary dyskinesia)
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