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Atrial Fibrillation (Complication (Risk of Heart failure 3x (Mechanism…
Atrial Fibrillation
Complication
Risk of stroke 5x
Risk of Heart failure 3x
Mechanism
Increase pressure in LA
Increase volume load
Valve dysfunction
Chronic stimulation of neurohumoral
Decrease quality of life
Prevalence
Most found arrythmia in clinical practice
1-2% --> terus meningkat
Pathophysiology
Factors
Perpetual factors
May not reconvert
Trigger factor
May re-convert spontaneously
Predisposing condition
Atrial remodelling
Disrupt electrical activity
Autonomic nerve
Sympathetic - Increase Ca+ intracellular
Parasympathetic - Shortening of effective refractory period
Increase excitability from pulmonary artery