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Anaemias (FBC (Bands:Immature leukocytes (ESR, EPO), Heamatocrit (% of RBC…
Anaemias
FBC
Heamatocrit
% of RBC in blood
MCH
Mean cell Hb: average mass of Hb/RBC
MCV
Mean cell volume
Bands:Immature leukocytes
ESR
EPO
Anaemia classification (All measured by MCV)
Normocytic
Acute blood loss
Haemolytic anaemia (HDN, AIHA)
Macrocytic
Liver failure/damage
Vit B12/Folate deficiency
Essential for DNA synthesis in reticulocytes
Megaloblastic anaemia
Malnutrition/absorption (pernicious anaemia)
Microcytic
Fe deficiency (hypochromic)
Sideroblastic anaemia (Failure to incorporate Fe)
Alcohol, malabsorption
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Multipotent haematopoietic stem cell
Lymphoid lineage
T+B cells
NK cells
Plasma cells
Myeloid lineage
Megakarocyte
Platelets
Erythroblasts
Reticulocyte
RBC
Leukocytes +MO