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IMMUNE SYSTEM (3 Layers of Immune Defense (Physical & Chemical…
IMMUNE SYSTEM
Human Lymphatic System
Primary Lymphoid Organs
production of white blood cells
Thymus
development of T cells
Bone Marrow
source of stem cells
source of blood cells
3 blood cell lineages
Myeloid
innate immune cells(4)
4 more items...
Erythroid
red blood cells
Lymphoid
B and T lymphocytes(adaptive)
NK cells(innate)
Secondary Lymphoid Organs
sites where immune responses are initiated
Lymph Nodes
filters lymph fluid from blood and tissues
located along lymphatic vessels
Spleen
blood-borne diseases: site of initiation
3 Layers of Immune Defense
Physical & Chemical barriers
Skin
Chemical Defences
Antimicrobial peptides(defensins)
Lysozymes
Sebum
Salt
Mucous Membranes
muscociliary escalator: goes back up to the mouth
Gastrointestinal tract
low pH(stomach)
antimicrobial peptides(defensins)
bile(breaks bacteria cell walls)
digestive enzymes
Tears
lysozyme
flushing action
Urogenital tract
lysozyme
low pH
high osmolarity
prevents microbial growth
Arm1: Innate Immune System
Inflammation
Arm2: Adaptive immune system