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Thesis Ideas (Brain Computer Interface (Coma Patients (amplify signals to…
Thesis Ideas
Brain Computer Interface
BCI that is charged by the brain's electrical activity
optogenetics in BCIs
implantablwe material to mimic naive brain electrical activity after TBI
Inject NPs that only release drug when BCI sends signal
Coma Patients
amplify signals to reach the brain
record signals to relay intent
Materials for Immune Modulation After TBI
Materials for Stem Cell Niches (UNDIFFERENTIATED)
Things to look into/Papers
Immune regulation after TBI
Lymphopoenia of Tumors
Can Immune suppressent activities of tumors guide Immune regulation of TBI?
cyclosporine A
Nanoparticle-releasing Material
Particles
mimic pathogens for easy uptake
release cytokines (e.g. IL-4 and IL-13) to influence macrophages to release anti-inflamatory factors (M2)
Material
Scaffold to release nanoparticles
Provide a suitable environment for neurons to grow
Finding my Project
What is being done?
What is our lab doing?
What opportunites exist for new materials/machines?
BCI-Immune Regulation Overlap
Magnetic Resonance Guided Implantation of "stealth" electrodes
Papers
Takashi "ultra-small" electrode placement (Nature materials)
Sui
Pituitary Diagnostics/Regulation after TBI
Blood Brain Barrier Recovery