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Growth regulation (RAS mutation (in its inactive state it is bound to a…
Growth regulation
RAS mutation
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RAS deactivates by the action of GTPase activity which breaks down the GTP to GDP with a protein called GTPase accelerating protein
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if RAS become mutated GTP may not be able to break down. so it bound to the RAS protein and it is permanently active leading uncontrolled cell division
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HER2
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tests
FISH test -The Fluorescence In Situ Hybridization test finds out if there are too many copies of the HER2 gene in the cancer cells
IHC test -the ImmunoHistoChemistry test finds out if there is too much HER2 protein in the cancer cells.
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