Please enable JavaScript.

Coggle requires JavaScript to display documents.

Compare and contrast the biochemical properties, structure and functions…

- - - - main steps involved in cell migration
        
        adhesion
        
        formation of focal adhesion at points of attachment
        
        Retraction
        
        retraction fibre elongates and ruptures
        
        Extension
        
        lamellipodia attaches
      - cell movement is controlled by proteins such as Arp2/3 complex which controls the branching of actin filaments and Rho GTPases regulates lamellipodia
    - - microfilaments need to be dynamic in the contractile ring
      - contractile ring is important for the regulation of cell division
        
        actin and myosin make up the contractile ring which happen before cytokinesis
        
        contractions are due to filament sliding to form the cleavage furrow which leads to the formation of two daughter cells
    - - bundle networks of microfilaments cell stress fibres they can be stained using actin antibodies
      - very dynamic during cell migration and changes in cell shape due to new attachment points that cells migrate
    - - thin microfilamnets have stable arrays in muscle
      - its stable because they need to responded very quickly to have that structure
      - filament sliding thin filaments over the thick filaments this leads to muscle contraction which is regulated by calcium
        
        calcium binds to a complex proteins troponin tropomysin complex
        
        troponin is made up of three components troponin I, T and C
        
        troponin C is what binds to the calcium. when calcium binds the tropomyosin blocks the myosin binding site in the microfilament when calcium levels are low
- - - - they bind on the negative end and grow on the positive end