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Compare and contrast the biochemical properties, structure and functions…
Compare and contrast the biochemical properties, structure and functions of microtubules and microfilaments
Functions
Microfilaments
Cell migration
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cell movement is controlled by proteins such as Arp2/3 complex which controls the branching of actin filaments and Rho GTPases regulates lamellipodia
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Cell shape
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very dynamic during cell migration and changes in cell shape due to new attachment points that cells migrate
Contractility
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filament sliding thin filaments over the thick filaments this leads to muscle contraction which is regulated by calcium
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troponin is made up of three components troponin I, T and C
troponin C is what binds to the calcium. when calcium binds the tropomyosin blocks the myosin binding site in the microfilament when calcium levels are low
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