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Compare and contrast the biochemical properties, structure and functions…

- - - - forms the mitotic spindle
        
        evidence: anti tubulin antibodies stain the mitotic spindle.
        
        evidence: antibody staining shows that tubulin forms the mitotic spindle fibres
      - Colchicine drug disrupts the mitotic spindle and stops cell division by destablizing the microtubules
        
        the drug binds to a protein called tubulin. which the protein that forms the core the mircotubule : structure
      - Centriole is made up of triplets of microtubules
    - - Microtubules are made up to form cilla and flagella
      - arrangement of microtubules is 9 + 2
        
        motor proteins are in microtubules
        
        motor protein kinesin and dynein. motor proteins have a cytoskeleton binding domain and a cargo binding domain
        
        dynein break down ATP and uses that energy to help the movement of flagella and cilia
    - - cell shape and interacellular transport is a role that microtubules play a part in the formation of nerve cells
      - microtubules allow proteins to been transported along the nerve cell
      - Evidence: colchicine interves with the growth of axons therefore interve with the regulation of cell shape during development and repair
      - Microtubules assembly is important for the growth of axons which development key changes in cell shape
  - - - Evidence: immunohistochemical detection of intermediate filament proteins