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Viruses (Replication Cycle (Exiting the Host (Exocytosis (bud off the…
Viruses
Replication Cycle
Invasion of the Host
endocytosis for viruses with round membrane
Replication of Genetic Material
rely on machinery of host
Replication of Capsomere
rely on machinery of host
Formation of Viral Progeny
100s-1000s
Exiting the Host
Exocytosis
bud off the host
Lysis
destroy the host cell
Lysogensis
insert genetic material into the host
Components
Viral Genome
dsDNA
ssDNA
dsRNA
ssRNA
Protein Capsid
helical
polyhedral w/o tail
polyhedral w/ tail
round
Viral Mebrane
made up of viral and host material
Viral Enzymes
still dependent on the host for replication machinary
Human Influenza Virus H3N2
ssRNA, round protein capsid, has a round envelope, carries polymerase enzymes
early outbreak of the flu
this strain was left out of the flu vaccine
Vaccines
stimulate immune response to a ghost capsid
Lymphocytes
B lymphocytes
originate in bone marrow
T lymphocytes
created in bone marrow but migrate to thymus
WBC
memory cells
antigens