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TYPE 1 HYPERSENSATIVITY (Local Anaphylaxis
(localized to site of…
TYPE 1 HYPERSENSATIVITY
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TYPE 1: TESTING
1. Skin testing
(inexpensive, but may sensatize an atopic person to a new allergen
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3. BASOPHIL ACTIVATION TEST
Activated :fire:CD63 on surface detected by Flow Cytometry
(life-threatening allergies)
IMMUNOTHERPAY
- Allergy Shots = desensitize
IgE :arrow_right: IgG response (doesn't bind Mast Cells)
- Passive Anti-IgE
:pill: Xolair - prevents IgE binding FceR Mast Cells