Kidney and Renal function Drugs (Mechanism Of Action (Diuretics and…
Kidney and Renal function Drugs
Thiazide: Chlorothiazide, Chlorthiazide, Hydroflumethazone, Indapamide, Methychlothiazide and Polythiazide
Loop Diuretics: Bumetanide, Ethacrynic acid,Furosemide, Torsemide
Potassium Sparing: Amioloride, Eplerenone, Spironolactone, Triamtene
Carbonic Anhydrate Inhibitors: Acetazolamide, Dichlorphenamide, Metholozamide
Mechanism Of Action
Diuretics and thiazide diuretics, aldactone and osmotic agents can effect on the nephrons significantly alter electrolyte balance.
Diuretics promotes urine output by altering the manner in which kidney handles sodium.
Most diuretics produce diuretics by inhibiting the reabsorption of sodium in different segments of therenal tubular system.
Pulmonary oedema, hypertension, nephritic syndrome, Hypercalcaemia and hypercalciuria
It is contraindicated in patients with hypersensitivity and those with electrolyte imbalance.
They should be cautiously in anyone with renal disfunction as changes in blood and perfusion may further compromise the diseased kidney.
It is contraindicated in patient with hypotension and hypovolaemia
Keep the medication in the original container or packaging, tightly closed or sealed in a cool and dry place, away from direct sunlight.Expired must be discarded.
Too little potassium in the blood because of Potassium sparing diuretics
Low sodium levels
Increased blood sugar
Route Of Administration
Oral and IV route