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Detection of hormones (Prolactin cont'd (Dopamine deficiency…

- - - - Thyrotropin releasing hormone (TRH) released by hypothalamus and sent to pituitary which in turn releases thyroid stimulating hormone (TSH) which causes release of thyroxin
      - thyroid hormones play a vital role in regulating metabolic, heart and digestive functions, muscle control, brain development and bone maintenance
      - T4 converted to T3 by liver/kidneys
- - - - lots of prolactin produced when pregnant due to high oestrogen levels and post birth prolactin leads to lactation
- - - - binds to plasma membrane receptors causing modulation of ion channels or membrane transport proteins
    - - which alters transcription levels of a particular protein. The hormone binds to a particular nuclear binding site and induces transcription of target gene
- - - - Glucocorticoids
        
        Cortisol - affect carbohydrates, fat and protein metabolism
      - mineralocorticoids
        
        aldosterone - involved in regulation of electrolytes through fluids and salts
    - - Oestrogens - development of female characteristics and reproductive cylce
      - Progestogens - involved in menstrual cycle, pregnancy and embryogenesis
      - Androgens - Male characteristics , also present in females and kickstarts puberty