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Želudac (Th (st IV (target th (HER (ToGA (cis+5FU/cap), HR 0.74, OS+2.7 mj…

- - - - DIM Japan (Dutch, Italian,MRC)
    - - https://www.google.ba/search?q=dissection+gastric+cancer&source=lnms&tbm=isch&sa=X&ved=0ahUKEwiWqYeEtsbaAhXBKJoKHQPwCwoQ_AUICigB&biw=1229&bih=548#imgrc=9ffJVVNbsGTenM:
  - - - ACT, S1, 1000 pts, +OS
        
        https://www.youtube.com/watch?v=N8Xg_C2YmG0
      - CLASIC, CAPOX, 1000 pts, HR 0.66 za OS+
        
        https://www.youtube.com/watch?v=jgpJVI3tDbY
      - ITACA-S, 1000 pts, 5FU/LC vs FOLFIRIx4 -Doc/Cis, HR 0.98
  - - - McDonalds int 0116, 560 pts, 5FU/LC+RT vs obs, OS 35 vs 27 mj
        
        https://www.youtube.com/watch?v=WQjO1mMCPg4
        
        https://www.youtube.com/watch?v=adKct96KXzM
        
        studije
        
        krt vs KT adj
        
        ARTIST, DFS=, +LČ DFS u krt, kt-XPx6; XPx2KRT+XpaXPx2
        
        https://www.youtube.com/watch?v=3eKBiEeag1A
        
        CRITICS, 800 pts, ECC/EOCx3 preop-OP-ECC/EOC vs KT (cis tj+kape)+RT45Gy/25x, OS krivulje iste
        
        http://sci-hub.tw/10.1016/S1470-2045(18)30153-0
        
        https://www.youtube.com/watch?v=O8Hfd145nRg&t=174s
      - CALGB 80101, ECF vs 5FU/LV plus RT, OS jednak
        
        https://www.youtube.com/watch?v=xd8QnwYXkfU
  - - - ACORD 07, Francuska, HR 0.66 +OS
        
        https://www.youtube.com/watch?v=fnJ_BPLcP5c
      - STO03, ECX+/- bev, više AE, OS isti
        
        https://www.youtube.com/watch?v=y4hpWTnaic0
      - MAGIC, 500p, ECF 3x2, pCR0
        
        https://www.youtube.com/watch?v=70U2yybKhKg
      - FLOT 4 (FLOTx4 -op-FLOTx4), želudac, GEJ, 70pts, OS 35 vs 50 mj za FLOT-u, HR 0.77
        
        https://www.youtube.com/watch?v=fOK3RHZ5Jhw
        
        novi klinci
        
        HER
        
        INOVATION, FLOT/FOLFOX +/- tras ili Tras+pert
        
        https://www.youtube.com/watch?v=Vdup9KRHcX4
        
        PETRARKA, FLOT +/- tras/pert
        
        https://www.youtube.com/watch?v=Qh_MlrKrlSk
        
        u tijeku
        
        Atezol
        
        perio FLOT+Atezol- DANTE
        
        https://www.youtube.com/watch?v=Q-5DVUtSnoY
  - - - mono vs kombo
        
        meta analiza, HR 0.83 OS+
      - studije
        
        3 vs 3
        
        FAMTX vs ECF, +OS
        
        MCFvsECF, 0OS
        
        REAL-2
        
        V325
        
        FAMTXvsELFvsCF, = rezultati
        
        faza 2
        
        FOLFIRI, FOLFOX vs ECF, = rezultati, <AE
    - - RT
      - laser
      - OP
      - stent
    - - ToGA
    - - Korejska studija, Irnio vs Doce VS BSC, +OS
      - ramucirumab
        
        REGARD
        
        https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61719-5/abstract
        
        RAINBOW
        
        https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)70420-6/abstract?code=lancet-site
    - - HER
        
        ToGA (cis+5FU/cap), HR 0.74, OS+2.7 mj
        
        LOGIC (Ox+cap), OS +1.7 SSOS
        
        TITAN, 2L, pakl, OS+2.1 SS
        
        GATSBY, TDM1 vs taxani, nSS
      - VEGR, bev, AVAGAST, HR0.87, nSS
      - EGFR
        
        cet, EXPAND, nSSS OS
        
        REAL 3, pan, neg
      - HGF (hepatocit faktor growth), rilo, RILOMET,neg te METAGASTRIC (FolFOX+Onartuzumab)
        
        https://www.youtube.com/watch?v=J-zHGF7Jb_o
      - https://www.youtube.com/watch?v=aPj0QeaZnNk
    - - pembro
        
        KN059, pembro, 260 pts, RR 12%
        
        https://www.youtube.com/watch?v=8p5pkbMoQs0
        
        http://ascopubs.org/doi/abs/10.1200/JCO.2017.35.15_suppl.4003
      - KN 012
        
        https://www.youtube.com/watch?v=aqXVleS7Vl0
        
        https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)00175-3/abstract?code=lancet-site
  - - - GITSG
- - - - 4 podtipa
        
        MEGS (C): MSI, EBV, GS, CIN
        
        https://www.youtube.com/watch?v=jMbWFuEsmTY
        
        https://www.google.ba/search?q=gastric+cancer+molecular+subtypes&source=lnms&tbm=isch&sa=X&ved=0ahUKEwiHncvKpt3aAhXGx6YKHd9PC2EQ_AUICigB&biw=1229&bih=587#imgrc=OZsTTFOZC1JzHM:
    - - https://www.google.ba/search?q=type+a+blood+and+gastric+cancer+pathophysiology&source=lnms&tbm=isch&sa=X&ved=0ahUKEwj-n9Ovit3aAhVDEpoKHUngCKgQ_AUICigB&biw=1229&bih=587#imgrc=Nj-j7S9BbuTVdM:
  - - - likalizacija