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Immunology (. (Innate (External barriers, Antimicrobial agents, Pathogen…

- - - - Macrophages
        
        long living
    - - most abundant
      - short living
  - - - develop in Thymus
      - intracellular pathogens
        
        type 1 helper T cells
      - B cell regulation
        
        type 2 helper T cells
      - host cell destruction
        
        cytotoxic T cells
      - development of immunity
        
        regulatory T cells
      - TCR - T cell receptor for antigen recognition
        
        cytokine secretion
    - - develop in bone marrow
      - antibody production
      - immunoglobulins
        
        on cell surface
        
        when antigen met
        
        plasma cell
        
        immunoglobulin secretion
        
        opsonisation
    - - also called natural killer cells
        
        recognise surface changes in infected or tumorous cells
        
        cytotoxic
    - - damage of large extracellular parasites
        
        cytotoxic
- - - - Activated by antibodies or mannose binding lectin
    - - Complement proteins directly opsonise microorganism
  - - - IFNa & IFNb
        
        released by cells with viral infection
      - IFNg
        
        released by Th1 activated cells
    - - released by T cells, mononuclear phagocytes, tissue cells
      - commonly induce growth and division
    - - differentiation and division of bone marrow stem cells
    - - direct movement of leukocytes across the body
    - - mediating inflammation
      - mediating cytotoxic reactions
    - - cell division and tissue repair
- - - - Epitope - a part of antigen antibody binds
    - - presentation of intracellular peptides
      - APC antigen presenting cells
        
        dendritic cells, macrophages, B cells
        
        presentation of antigens in MHC to activate T cell responses
      - TCR receptor recognises