Oliguia, anuria (less than 0.5ml/kg/hr for greater than 6 hrs, tachycardia, hypertension, hypotension, bibasilar crackles, irritability, drowsiness, confusion, altered level of consciousness, bleeding abnormalities, ecchymoses, purpura, dry, pruritic skin, maculopapular rash, dry mucous membranes, uremic breath odor, seizures, myoclonus, retinopathy, keratis, iritis, uveitis, cardiac arrythmias ( a fib, peaked t wave), limb ischemia, edema