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Immune System (Innate Immunity (Cellular Barriers (Macrophages, NKCells,…

- - - - Stimulate or Inhibit the differentation, proliferation or funtion of immune cells
- - - - B-lymphocyte
        
        Memory B-cell
        
        Record infectious agent
        
        Plasma cell
        
        Antibody
        
        Ig G
        
        4 subclasses
        
        Most abundent
        
        can transfer along placenta
        
        Ig A
        
        2 subclasses
        
        Dimer
        
        Ig M
        
        Agglutination in primary response
        
        Pentameric molecule
        
        Ig E
        
        Sensitive to parasite and allergic
        
        Bound with mast cell and basophils
        
        Ig D
        
        Involved in B-cell develop
    - - T-lymphocyte
        
        Suppressor T-cell
        
        Modulate the immune system
        
        Prevent autoimmune disease
        
        CD4, FOXP3, CD25
        
        Prevent autoimmune disease
        
        Helper T-cell
        
        Release T-cell cytokines
        
        Suppress and regulate immune respond
        
        CD4+, CD154, CD40L
        
        Cytotoxic T-cell
        
        CD8+
  - - - Active
        
        By vaccination
        
        Contain antigen
        
        prevent causing symptoms of disease
      - Passive
        
        Short-term immunization
        
        Administered in the form of blood plasma
        
        involved antibody
    - - Active
        
        Primary immune response
        
        occur when expose to pathogen
      - Passive
        
        Maternal
        
        transfer during pregnancy through placenta
        
        Maternal antibody
        
        Breast milk