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Vasculitis (Small Vessel Vasculitis (Henoch-Schonlein Purport (Treatment,…

- - - - C shaped: nasopharynx, lungs, and kidneys
      - middle-aged male
        
        sinusitis, nasopharyngeal ulcer bilateral nodular infiltrates
        
        Rapidly Progressing Glomerulonephritis
        
        hematuria
    - - cyclophosphamide
      - steroids
      - relapses common
  - - - Similar to Weceners but no nasopharyngeal involvement and granulomas are absent
    - - corticosteroids
      - cyclophosphamide
  - - - steroids if severe
- - - - multiple organs, but lungs are spared
        
        hypertension: renal artery involvement
        
        abdominal pain w melena : mesenteric artery involved
        
        skin lesions
        
        neurologic disturbances
      - young adults:
      - lesions at various stages: transmural inflammation w fibroid necrosis
    - - corticosteroids
      - cyclophosphamide
  - - - Nonspecific signs w palms and soles rash
        
        Coronary artery
        
        thrombosis w myocardial infarction
        
        aneurysm w rupture
    - - Aspirin
      - IVIG
  - - - stop Smoking
- - - - CAROTID ARTERY
        
        ophthalmic artery: visual disturbances
        
        jaw arteries: jaw claudication
        
        temporal artery: headache
        
        elevated ESR
        
        polymyalgia rheumatica
    - - giant cells w intimal fibrosis
      - lesions are segmental, so negative biopsy does not exclude disease
    - - corticosteroids
  - - - AORTIC ARCH AT BRANCH POINTS
        
        ESR elevated
        
        Asian females
        
        Pulseless disease: weak pulses in upper extremity
    - - corticosteroids