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enzyme inhibitors (competitive inhibition (examples (statins - inhibitor…

- - - - enzyme cannot carry out function - said to be inhibited
        
        inhibitor and substrate molecules present in a solution compete with each other to bind to active sites of enzymes catalysing reaction
        
        reduce number of substrate molecules binding to active sites in given time - slow down rate of reaction
  - - - increased substrate concentration - much more substrate than inhibitor that original Vmax can be reached
  - - - prescribed to help people reduce blood cholesterol concentration - high blood cholesterol levels can lead to heart disease
- - - - active site no longer has complementary shape to substrate - unable to bind to enzyme
        
        enzyme cannot carry out function - said to be inhibited
  - - - increasing concentration of inhibitor decreases rate of reaction further as more active sites become unavailable
- - - - enzyme which catalyses initial breakdown of glucose molecule (PFK) is inhibited by ATP
        
        ATP regulates its own production