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Lecture 9 (Classification of Hypoxias (Pathologies that cause hypoxia…

- - - - Thickened alveolar membrane slows gas exchange. Loss of lung compliance may decrease alveolar ventilation
        PO2 normal or low in alveoli and low in capillary
    - - Fluid in interstitial space increases diffusion distance. Arterial PCO2 may be normal due to higher CO2 solubility in water.
        PO2 normal in alveoli and PO2 low in capillary
    - - Destruction of alveoli means less surface area for gas exchange
        PO2 is normal or low in alveoli and low in capillary
    - - Increased airway resistance decreases alveolar ventilation
        Bronchiole constricted, PO2 is low in alveoli and in capillary
- - - - Amount of fluid
      - Barrier thickness
  - - - Airway resistance
      - Lung compliance
      - Rate and depth of breathing