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Lecture 8 (Surface Tension (Lung volume vs Changes in pressure (pressure…
Lecture 8
Surface Tension
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Surface tension and force of gravity balanced=floating
Alveoli behave like little bubbles
Big bubbles, blow slow, pressure is low
Small bubbles, blow hard, pressure is high
Law of Laplace
P=2x surface tension/radius of bubble
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Compliance and Elastance
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Lung disease related to compliance
High compliance disorder (also called obstructive lung diseases)
Emphysema
Reduced elastic tissue
Low elastance
Restrictive lung diseases
Low compliance (stiff)
Fibrotic Lung Disease (inelastic scar tissue-asbestos, silicon)
Respiratory Distress Syndrome (lack of surfactant) common in premature infant (lungs haven't developed fully)
Compliance: ability of the lung to stretch, effects work of breathing